Autoimmune polyendocrine syndrome type 2 is a form of autoimmune polyendocrine syndrome.
Autoimmune polyendocrine syndrome, type 2 (also known as "Schmidt's syndrome", or APS-II) is the most common form of the polyglandular failure syndromes. It is more heterogeneous and has not been linked to one gene. Rather, patients are at a higher risk when they carry a particular human leukocyte antigen genotype (DQ2, DQ8 and DRB1*0404). APS-II affects women to a greater degree than men (75% of cases occur in
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